A new animal study shows that low levels of adiponectin are associated with higher toxicity of sepsis whereas adequate adiponectin prevents sepsis.  Adiponectin levels are low in overweight people and being overweight is a risk factor for getting severe H1N1 swine flu.  Those with severe H1N1 swine flu have sepsis-like symptoms due to the toxicity and low oxygen condition produced by the infection.

Any flu tends to deactivate the anti-bacterial defense system setting the stage for secondary bacterial infection, including pneumonia.  The sepsis of pneumonia kills more people than the flu.  Sepsis also occurs from infections following surgery.  Overweight people are 2 ½ - 3 times more likely to die from sepsis following surgery.

Adiponectin is a hormone, like leptin, that comes from fat.  It is vital for assisting the proper function of insulin and preventing diabetes.  Thus, overweight individuals, especially diabetics, are likely to be low in adiponectin.  Why adiponectin prevents sepsis is at this time unknown.

Even overweight individuals can help get adiponectin on track by following the Leptin Diet.  When leptin is too high (leptin resistance) it is known to suppress adiponectin levels.  By correcting excess leptin problems adiponectin levels bounce back to a healthier level.
Various nutrients have been shown to support the production of adiponectin, including quercetin, DHA, magnesium, resveratrol, grape seed extract, mangosteen, banaba leaf, and likely many others.

Leptin is the commander and chief of all hormones.  It is structured as an immune system cytokine, indicating the significant impact of leptin on immunity.  In health, leptin and adiponectin rise in harmony.  It appears now that you not only want to accomplish this as part of weight management and healthy blood sugar function, but also to support healthy immunity.

Posted by Mitchell at 09:58 PM.

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